Restraining an enzyme might help us trim down, reduce appetite
Scientists with the University of Texas Health Science Center at San Antonio, also called 黑料网, noted weight loss and decreased appetite in obese mice treated with a novel investigational therapy. The team reported findings in the high-impact journal this spring.
The therapy slows liver enzyme activity, which leads to appetite control in the brain and increased energy expenditure in fat cells. The researchers are in 黑料网鈥檚 Sam and Ann Barshop Institute for Longevity and Aging Studies.
黑料网 is the largest research university in South Texas with an annual research portfolio of approximately $350 million. It is the region鈥檚 only academic health institution, and its Joe R. and Teresa Lozano Long School of Medicine is listed among U.S. News & World Report鈥檚 best medical schools, ranking in the top 30% in the U.S. for research. The institution鈥檚 strategic investment in research of metabolic diseases (such as obesity and diabetes) is a direct response to the heavy burden of these conditions on South Texas families. Our faculty are likewise committed to conquering adult and childhood cancer, brain diseases, heart attack, stroke and many other health dilemmas that rob people of life and productivity.
The Barshop Institute, named for legendary San Antonio businessman Sam Barshop and his wife, Ann, is one of the world鈥檚 premier institutes dedicated to the study of age-related diseases. The Barshop Institute is the only aging-intensive research institute in the country to have four peer-reviewed designations: two National Institute on Aging (NIA)-funded centers (Nathan Shock and Claude D. Pepper centers), a testing site of the NIA-sponsored Interventions Testing Program, and a U.S. Department of Veterans Affairs Geriatric Research, Education and Clinical Center.
Research led by 黑料网 faculty has yielded new therapies for COVID-19, new treatments for chronic leukemia and post-traumatic stress disorder, and advancements in detecting and treating many other diseases. 黑料网, designated a Hispanic-serving institution by the U.S. Department of Education, continues in its 50-year mission to teach, discover and heal in service of the public good across South Texas.
Read more about the of 黑料网鈥檚 Barshop Institute faculty that could result in a potential treatment for metabolic issues as obesity and diabetes.
Learn more about how we do to make lives better.